Pathogenesis of autoimmune disease
Pisetsky, D.S. Pathogenesis of autoimmune disease. Nat Rev Nephrol 19, 509–524 (2023). https://doi.org/10.1038/s41581-023-00720-1
- Autoimmune diseases lead to diverse patterns of inflammation and organ dysfunction.
- Autoantibodies are valuable markers for diagnosis, classification and of disease activity.
- Although T cells play a key part in disease, their assessment is challenging.
- Autoimmune disease reflects the interplay of genetic and environmental factors.
- Pre-clinical autoimmune disease provides a window of time for early or preventive treatment.